Global
Dextran
Market is expected to grow at a
positive CAGR in the predicted period. Dextran is a complex branched glucan
(Polysaccharide made of many glucose molecules) Composed of chains of varying
lengths (From 3 to 2000 kilodaltons). The straight chain consists of α-1,6 glycosides
linkages between glucose molecules, while branches begin from α-1,3 linkages.
Dextran
was discovered by Louis Pasteur as a bacterial product in wine but mass
production was only possible after the development by Allene Jeanes of a
process using bacteria. Dextran is now synthesized from sucrose by certain
lactic acid bacteria, the best-known being Leucon Stoc meteoroids and
Streptococcus mutants. Dental plaque is rich in dextran’s.
Medicinally
it is used as an antithrombotic (antiplatelet) to reduce blood viscosity, and
as a volume expander in hypovolemia. The physical and chemical things of
purified dextran’s differ contingent on the microbial strains from which they
are shaped and by the production method.
Dextran
has high water solubility and the solutions behave as Newtonian fluids.
Solution viscosity depends on concentration, temperature, and molecular weight,
which have a characteristic dispersal. The hydroxyl groups present in dextran
offer many sites for derivatization, and these functionalized glycol conjugates
represent an essentially unexplored class of biocompatible and environmentally
safe compounds.
Accumulative
consumer trend towards healthy and additive-free food has made dextran from
food grade lactic acid bacteria (LAB) an attractive solution. dextran’s are
homopolysaccharides of d-glucose produced by extracellular dextransucrase
liberated from LAB of the genera, viz., Leuconostoc, Lactobacillus,
Streptococcus, Weissella, and Pedi coccus. dextran have been known for their
viscosifying, emulsifying, texturizing, stabilizing attributes in food
applications.
Dextran
has the potential to be employed as a novel component swapping the commercial
hydrocolloids in bakery and other food industries. Prebiotic oligosaccharide manufacture
by hydrolysis of dextran is a rather new field, gathering research and
industrial attention.
Dextran
Market is segmented by class
1T1-T10, Class 2 T10-T70, and Class 3 Above T70.Class 1 dextran’s contain the α
(1→6)-linked D-glucopyranosyl backbone modified with small side chains of
D-glucose branches with α (1→2), α(1→3), and α(1→4)-linkage. The class 1
dextran’s varies in their molecular weight, spatial arrangement, type and
degree of branching, and length of branch chains, depending on the microbial
producing strains and cultivation circumstances. Isomaltose and isomaltotriose
are oligosaccharides with the class 1 dextran backbone structure. Class 2
dextran’s contain a backbone structure of alternating α (1→3) and α(1→6)-linked
D-glucopyranosyl units with α(1→3)-linked branches.
Class
3 dextran’s (mutants) have a backbone structure of consecutive α(1→3)-linked
D-glucopyranosyl units with α(1→6)-linked branches. One and two-dimensional NMR
spectroscopy techniques have been utilized for the structural analysis of
dextran’s. Dextran 70 is on the WHO Model list of Indispensable Medicines the
most significant medications wanted in a health system.
Based
on application, the Dextran Market is segmented into Pharmaceutical,
Agricultural, Food Industries and Others. Geographically, the Dextran Market
spans North America, Europe, Asia-Pacific, South America. Key players in the
dextran market include Pharma cosmos, PK Chemicals, Meito Sangyo, Polydex
Pharm, Jinyang Biological Pharmaceuticals, Biotech Beta Glucans, LB Nature
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